INTRODUCTION Doxorubicin is a cytotoxic anthracycline antibiotic. Doxorubicin can be used in single treatment or can be integrated in a combination therapy and is indicated for the treatment of various cancers such as: breast, lung, bladder, thyroid, gastric and ovarian carcinomas, osteosarcomas and soft tissue sarcomas, Wilms’ tumours, Hodgkin and non-Hodgkin lymphomas, neuroblastomas and acute[…]
Abstract From the time unknown, invention and innovation have been vital for human development. In the healthcare sector, pharmaceutical companies have worked extensively on developing new entities that have become therapeutic for diseases. However, these companies face problems with poor revenue generation; without revenue, they cannot develop new drugs. The problems are mainly due to[…]
1. Introduction The stories of impurities in drugs usually reach the public when a disaster happens – an enantiomeric impurity present in thalidomide (used to treat nausea in pregnant individuals) gained worldwide notoriety in 1962 when its teratogenic effect was discovered. As recently as 2009, at least 25 children died in Bangladesh after taking[…]