Abstract Therapeutic drug monitoring (TDM) involves measuring the serum level of a drug to ensure it is within the therapeutic window. It is essential for some drugs including the anticonvulsants such as phenytoin, carbamazepine and ethosuximide; the bronchodilator, theophylline and the tricyclic antidepressant, clomipramine. Current methods of analysis involve immunoassays and high performance liquid chromatography[…]